Taking AIM1 at prostate cancer invasion and metastasis

Progression to metastatic disease is the major cause of prostate cancer related death. Loss or mislocalization of AIM1 (aka CRYBG1), which regulates cytoskeletal remodeling, was shown to promote prostate cancer invasion and metastases. Read more about it in Haffner et al, Nat Commun, 2017. See also the press release and some of the media coverage of the findings.

Srinivasan (Vasan) Yegnasubramanian, M.D., Ph.D.
Assistant Professor of Oncology
Johns Hopkins University

Sidney Kimmel Comprehensive Cancer Center
Cancer Research Building II, Room 145
1550 Orleans Street
Baltimore, MD, 21231

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